A series of seminal papers in our field, selected and introduced by SSIB members and available to all.
The primary purpose is to provide students, postdocs and colleagues with papers that various SSIB members consider to be critical building blocks of our field. The “classics” provide important historical context, both on the concepts upon which their work and hypotheses were based and on the results and standards of interpretation that the authors considered critical. The commentaries provide perspectives linking the classics to current work and ongoing issues.
CLASSIC 29: Ann E. Kelley and Nucleus Accumbens ‘Supervision’ of the Hypothalamus
MALDONADO-IRIZZARRY, M. and KELLEY, A.E.
Glutamate receptors in the nucleus accumbens shell control feeding behavior via the lateral hypothalamus.
Journal of Neuroscience 15, 6779-6788, 1995.
STRATFORD, T.R. and KELLEY A.E.
Evidence of a functional relationship between the nucleus accumbens shell and lateral hypothalamus subserving the control of feeding behavior.
Journal of Neuroscience 19, 11040-11048, 1999.
Comments by Brian A. Baldo, (Jan. 18, 2023)
CLASSIC 1: Mayer and the Glucostatic HypothesisMAYER, J. Glucostatic mechanism of regulation of food intake. New England Journal of Medicine 249 : 13-16, 1953.
Comments by Barry Levin (November 1, 2013)
CLASSIC 2: Smith and Glucoprivic Feeding
SMITH, G.P. and A.N. EPSTEIN. Increased feeding in response to decreased glucose utilization in the rat and monkey. American Journal of Physiology 217; 1083-1087, 1969.
SMITH, G.P., J. GIBBS, A.J. STROHMAYER, and P.E. STOKES. Threshold doses of 2-deoxy-D-glucose for hyperglycemia and feeding in rats and monkeys. American Journal of Physiology 222; 77-81, 1972.
Comments by Gerard P. Smith (November 20, 2013)
CLASSIC 3: Curt Richter and the Behavioral Control of HomeostasisRICHTER CP, Total self-regulatory functions in animals and human beings. Harvey Lecture Series 38: 63-103; 1943.
Comments by Nori Geary (December 20, 2013)
CLASSIC 4: David Brown, Stephen Holtzman and the Opioidergic Control of EatingDAVID R. BROWN & STEPHEN G. HOLTZMAN. Suppression of deprivation-induced food and water intake in rats and mice by naloxone. Pharmacol Biochem Behav. 1979;11(5):567-573
Comments by Allen S. Levine (January 15, 2014)
CLASSIC 5: John Brobeck, and the Hypothalamic Control of Eating (I)
BROBECK, J. R., TEPPERMAN, J., and LONG, C. N. H. Experimental hypothalamic hyperphagia in the albino rat. Yale Journal of Biology and Medicine 15: 831-853, 1943.
Comments by Harry R. Kissileff, St. Luke’s/Roosevelt Hospital and Columbia University
CLASSIC 6: Bal Anand and John Brobeck and the Hypothalamic Control of Eating (II)
ANAND B.K., BROBECK, J.R.
Hypothalamic control of food intake in rats and cats. Yale Journal of Biology and Medicine 24: 123-140; 1951.
Comments by Tim Moran (March, 2014)
CLASSIC 7: Gibbs and Smith and CCK Satiation
GIBBS, JAMES AND GERARD P. SMITH
Cholecystokinin and satiety in rats and rhesus monkeys. American Journal of Clinical Nutrition 30: 758-761, 1977.
Comments by Gerard P. Smith and James Gibbs (May, 2014)
CLASSIC 8: P. T. Young and the Hedonic Control of Eating
Psychologic factors regulating the feeding process. American Journal of Clinical Nutrition 5: 154-161, 1957.
Comments by Kent Berridge (July 2014)
CLASSIC 9: Harvey Grill and Ralph Norgren: Oral-Facial Reactivity to Gustatory Stimuli
HARVEY J. GRILL and RALPH NORGREN
The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats. Brain Research 143: 263-279, 1978
Comments by Harvey Grill (December 2014)
CLASSIC 10: Ed Stricker, Joe Verbalis and Oxytocin
MONICA J. McCANN, JOSEPH G. VERBALIS and EDWARD M. STRICKER
LiCl and CCK inhibit gastric emptying and feeding and stimulate OT secretion in rats. American Journal of Physiology 256: R463-R468, 1989.
Comments by Linda Rinaman (April, 2015)
CLASSIC 11: James Olds and Pleasure in the Brain
Brain stimulation and the motivation of behavior. Progress in Brain Research 45: 401-426, 1976.
Comments by Ralph Norgren (June, 2015)
CLASSIC 12: George Wolf and Innate Mechanisms of Sodium Appetite
Innate mechanisms for regulation of sodium intake. In: Olfaction and Taste., edited by Carl Pfaffman. New York: Rockefeller University Press, 1969; pp 548-553.
Comments by Alan C. Spector (June, 2015)
CLASSIC 13: Garvin L. Holman and Post-Oral Flavor Preference Conditioning
GARVIN L. HOLMAN
Intragastric reinforcement effect. Journal of Comparative and Physiological Psychology, 1968, 69, 432-441.
Comments by Anthony Sclafani (February, 2016)
CLASSIC 14: Porte and Woods and Insulin as an Adiposity Signal
WOODS, S.C., E.C. LOTTER, L.D MCKAY, AND D. PORTE, JR.
Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nature 282: 503-505, 1979.
Comments by Stephen Woods (April, 2016)
CLASSIC 15: Gordon C. Kennedy and the Lipostatic Control of Eating
KENNEDY, Gordon C.
The Role of Depot Fat in the Hypothalamic Control of Food Intake in the Rat. Proc R Soc B Biol Sci 1953;140:578–592.
Comments by David Levitsky, Cornell University (September, 2016)
CLASSIC 16: Stanley Schachter and Obesity and Eating
Obesity and Eating. Science, New Series, Vol. 161, No. 3843 (Aug. 23, 1968), pp. 751-756.
Comments by TaShauna U. Goldsby Ph.D., Cynthia M. Kroger Ph.D., and David B. Allison Ph.D. (January, 2017)
CLASSIC 17: Herman and Polivy’s Restrained Eating Model
HERMAN, C. PETER AND MACK, DEBORAH
(1975). Restrained and unrestrained eating. Journal of Personality, 43, 647-660.
Comments by Michael R. Lowe, Ph.D. (Oct, 2017)
CLASSIC 18: Jack Davis and David Wirtshafter on settling points and parsimony
WIRTSHAFTER, DAVID, AND DAVIS, JOHN D.
Set points, settling points, and the control of body weight. Physiology and Behavior 19: 75-78, 1977.
Comments by Nori Geary, May 2018
CLASSIC 19: Steve Fluharty and Alan Epstein on the control of salt appetite by angiotensin and aldosterone
FLUHARTY, STEVEN J, AND EPSTEIN, ALAN N.
Sodium appetite elicited by intracerebroventricular infusion of angiotensin II in the rat: II.Synergistic interaction with systemic mineralocorticoids.
Behav Neurosci 97: 746-758, 1983 Oct;97(5):746-758.
Comments by Derek Daniels, October, 2018
CLASSIC 20: Trace Conditioning in Taste Aversion Learning
SMITH J.C. and ROLL D.L.
Trace conditioning with x-rays as an aversive stimulus.
Psychonomic Science 9; 11-12, 1967.
Comments by Alan C. Spector, March, 2019
CLASSIC 21: Dietary Fat Content and Caloric Intake
Lauren Lissner, David A. Levitsky, Barbara J. Strupp, Heidi J. Kalkwaf, Daphne A. Roe.
Dietary fat and the regulation of energy intake in human subjects.
The American Journal of Clinical Nutrition 46: 886-892, 1987.
Comments by Kees de Graaf, April 2019
CLASSIC 22: Stunkard and the Night Eating Syndrome
STUNKARD AJ, GRACE WJ, WOLFF HG.
The night-eating syndrome—a pattern of food intake among certain obese patients.
Am J Med. 1955;19(1):78–86.
Comments by Allan Geliebter, August 2019
CLASSIC 23: John de Castro and the Social Facilitation of Eating
de CASTRO, JOHN M.
Family and friends produce greater social facilitation of food intake than other companions.
Physiology & Behavior 56: 445-455, 1994.
Comments by Suzanne Higgs, Helen Ruddock, Lenny Vartanian and Jeff Brunstrom, September, 2019
CLASSIC 24: Barbara Rolls and Sensory Specific Satiety and Variety
BARBARA J. ROLLS, EDMUND T. ROLLS, EDWARD A. ROWE, AND KEVIN SWEENEY
Sensory specific satiety in man.
Physiology & Behavior 27: 137-142, 1981.
With an interview of Barbara Rolls by Marion Hetherington, January 2020
CLASSIC 25: The Three Factor Eating Questionnaire to measure dietary restraint, disinhibition and hunger
STUNKARD, ALBERT J, AND MESSICK, SAMUEL
The Three Factor Eating Questionnaire to measure dietary restraint, disinhibition and hunger.
Journal of Psychosomatic Research, 29, 71-83.
Comments by Margriet S. Westerterp-Plantenga, Ph.D. (Oct, 2020)
CLASSIC 26: Ilene Bernstein and conditioned taste aversions in humans
ILENE L. BERNSTEIN (1978)
Learned taste aversions in children receiving chemotherapy.
Science 200: 1302-1303.
Comments by Mitchell Roitman (February 2022).
CLASSIC 27: Harry Kissileff and measuring human eating in the laboratory
KISSILEFF, HARRY R, KLINGSBERG, GARY, and Van ITALLIE, THEODORE B. (1980)
Universal eating monitor for continuous recording of solid or liquid consumption in man.
American Journal of Physiology 338: R14-R22.
With an interview of Harry Kissileff by Kathleen L. Keller (March, 2022)
CLASSIC 28: Douglas Coleman’s Parabiosis Studies in Obese and Diabetic Mice
DOUGLAS L. COLEMAN and KATHERINE HUMMEL (1969)
Effects of Parabiosis of Normal with Genetically Diabetic Mice
American Journal of Physiology 217, 1298-1304
DOUGLAS L. COLEMAN (1973)
Effects of Parabiosis of Obese with Diabetes and Normal Mice
Diabetologia 9, 294-298